The McLaren driver, who only started 15th on the grid after a disappointing qualifying, lost control of his car at turn 12 of the new Las Vegas Strip Circuit.
The Brit diverted right, straight into the wall and losing a tyre, before spinning into the barrier.
Norris, while breathing heavily, did let his engineer know “I’m OK.”
Max Verstappen took the lead from Charles Leclerc at turn one but failed to pull away from the Ferrari.
The Dutchman was then hit with a five-second penalty for that move at lights out, forcing Leclerc off the track.
Leclerc took the lead on track anyway, on lap 16, while Verstappen dived into the pits.
More to follow…